Sheep anti Mouse LFC
Catalogue Number: X1089P-NMB
| Manufacturer: | Nordic MuBio |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Rho guanine nucleotide exchange factor 2, ARHGEF2 |
| Shipping Condition: | RT |
| Unit(s): | 250 ug |
| Host name: | Sheep |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Antibody developed using protein corresponding to amino acids 2 to 447 of the Lfc protein fused to GST. |
| Application: | IF, IP, WB |
Description
Description: Lfc is a 118 kDa protein discovered in a screen for oncogenes in NIH 3T3 cells. Lfc is a signaling protein related to Lbc and is part of the Dbl family of proteins. Lfc is a guanine-nucleotide exchange factor (GEF) for the Rho family of small GTPases. Lfc has also been shown to be upstream of the serine-threonine kinase JNK. Lfc has also been shown to mediate the activation of the Rac signaling pathway.
Additional Text
Gene ID
9181
Gene Name
ARHGEF2
Uniprot ID
Q92974
Purification
Ammonium Sulfate Precipitated
Antibody Clonality
Polyclonal
Application Notes
Detects Lfc in mouse tissues by immunoprecipitation-Western blot at 4 µg/ml. Detects a 118 kDa band in mouse tissue extracts corresponding to wild-type Lfc. Can also be used in immunofluorescence assays. Optimal concentration should be evaluated by serial dilutions.
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations