Mouse anti Human Proximal Nephrogenic Renal Antigen, cln PN-15 (66.4.C2)
Catalogue Number: X1234M-EXA
| Manufacturer: | ExAlpha |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 66.4.C2 |
| Isotype: | IgG2b |
| Immunogen: | |
| Application: | IHC-P, IHC-Fr |
Description
Description: This antibody reacts with a glycoprotein of 200 kDa present in proximal renal tubules. The antigen is a carbohydrate in nature and retained in formalin fixed paraffin embedded tissues. Other normal tissues that display the antigen include breast, parathyroid glands and epididymis. Among renal carcinomas, 93% of primary and 84% of metastatic carcinomas are positive for this antigen. Relatively few other tumor types are positive: breast cancers, teratocarcinomas and parathyroid adenomas.
Additional Text
Gene ID
768
Gene Name
CA9
Uniprot ID
Q16790
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal
Application Notes
This antibody can be used for the differential diagnosis of carcinomas by Western blotting and immunohistochemistry on frozen and paraffin-embedded tissues. Protease digestion prior to antibody incubation enhances staining of tissue sections. Optimal concentration should be evaluated by serial dilutions.
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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