Mouse anti Human Heat Shock Protein 27

Catalogue Number: X1264M-EXA

Manufacturer:ExAlpha
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: G3.1
Isotype: IgG1
Immunogen:
Application: ELISA, ICC, IHC-P, IP, WB, IHC-Fr, EIA

Description

Description: HSP27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. HSP27 synthesis is induced by elevated temperature as well as estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosphilia HSPs and mammalian alpha-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore, HSP27 may be useful in classifying various hormone sensitive tumors.

Additional Text

Gene Name

HSPB1

Gene ID

3315

Uniprot ID

P04792

Purification

Protein A/G Purified

Antibody Clonality

Monoclonal

Application Notes

This antibody can be used for immunohistochemistry and immunocytochemistry on frozen and paraffin-embedded tissue sections as well as for ELISA, immunoprecipitation and Western blot. Optimal concentration should be evaluated by serial dilutions.

Storage Note

Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles