Rat anti Human IL-10
Catalogue Number: X1305M-EXA
| Manufacturer: | ExAlpha |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | rat anti human Interleukin-4, IL-4, unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | R.625 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: IL-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. It defects in IL10 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease.
Additional Text
Gene Name
IL10
Gene ID
3586
Uniprot ID
P22301
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal
Application Notes
Optimal concentration should be evaluated by serial dilutions.
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations