Rat anti Human IL-10

Catalogue Number: X1305M-NMB

Manufacturer:Nordic MuBio
Type:Monoclonal Primary Antibody - Unconjugated
Alias:rat anti human Interleukin-4, IL-4, unconjugated
Shipping Condition:RT
Unit(s): 100 ug
Host name: Rat
Clone: R.625
Isotype: IgG1
Immunogen:
Application: FC, IF

Description

Description: IL-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. It defects in IL10 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease.

Additional Text

Gene Name

IL10

Gene ID

3586

Uniprot ID

P22301

Purification

Protein A/G Purified

Antibody Clonality

Monoclonal

Application Notes

Optimal concentration should be evaluated by serial dilutions.