Lysophosphatidic Acid Receptor 2 (EDG4) CT

Catalogue Number: X1573B-EXA

Manufacturer:ExAlpha
Type:Blocking Peptides
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name:
Clone:
Isotype:
Immunogen:
Application: WB, Inh-Fun

Description

Description: EDG4 (LPA2) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG4 (LPA2) is lysophospholipid. There are 6 known members of the EDG receptor family and they are implicated in mediating growthrelated effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG4 (LPA2) is expressed in testes, ovarian tumor and leukocyte containing tissues.

Additional Text

Gene ID

9170

Gene Name

LPAR2

Uniprot ID

Q9HBW0

Application Notes

For use with EDG4 (LPA2) (NT) polyclonal antibody (Cat. No. X1570P).

Storage Note

Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles