Sphingosine 1-Phosphate Phosphatase 1

Catalogue Number: X1644B-NMB

Manufacturer:Nordic MuBio
Type:Blocking Peptides
Shipping Condition:RT
Unit(s): 50 ug
Host name:
Clone:
Isotype: IgG
Immunogen:
Application: Inh-Fun

Description

Description: Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. Regulation of hS1Pase1 with the resultant changes in cellular and secreted S1P has important implications in cell proliferation, angiogenesis and apoptosis.

Additional Text

Uniprot ID

Q9BX95

Gene ID

81537

Gene Name

SGPP1

Application Notes

For use with Sphingosine 1-Phosphate Phosphatase 1 polyclonal antibody (Cat. No. X1636P).

Storage Note

Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles