Sphingosine 1-Phosphate Phosphatase 2
Catalogue Number: X1645B-NMB
| Manufacturer: | Nordic MuBio |
| Type: | Blocking Peptides |
| Shipping Condition: | RT |
| Unit(s): | 50 ug |
| Host name: | |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | |
| Application: | Inh-Fun |
Description
Description: Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. SPPase2 is localized to the endoplasmic reticulum. The enzymatic activity and localization of SPPase2 are similar to SPPase1. The tissue expression of SPPase2 was different from that of SPPase1. SPPase2 is an important member of the SPPase family which play a role in attenuating intracellular S1P signaling.
Additional Text
Gene ID
130367
Gene Name
SGPP2
Uniprot ID
Q8IWX5
Application Notes
For use with Sphingosine 1-Phosphate Phosphatase 2 polyclonal antibody (Cat. No. X1637P).
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations