Sphingosine Kinase 1, Long Form, Rat
Catalogue Number: X1875B-EXA
| Manufacturer: | ExAlpha |
| Type: | Blocking Peptides |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Application: | Blk, Inh-Fun |
Description
Description: Rat sphingosine kinase 1 catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (spp)(sphingosine + ATP = sphingosine 1-phosphate + ADP), a lipid mediator with both intra- and extracellular functions. also acts on d-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as d,l-threo-dihydrosphingosine, n,n-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol. The long form of sphingosine kinase 1, an N-terminal extension, is responsible for FceRI-mediated calcium mobilization and may play a role in other ligand mediated signaling events.
Additional Text
Application Notes
Blocking peptide for use with rat Sphingosine kinase 1, long form antibodies (X1848P & X2038P).
Uniprot ID
Q1HGK5
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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