Sphingosine Kinase 1 (Ser225), Mouse
Catalogue Number: X1877B-NMB
| Manufacturer: | Nordic MuBio |
| Type: | Blocking Peptides |
| Shipping Condition: | RT |
| Unit(s): | 50 ug |
| Application: | Inh-Fun |
Description
Description: Sphingosine kinase 1 catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (spp)(sphingosine + ATP = sphingosine 1-phosphate + ADP), a lipid mediator with both intra- and extracellular functions. also acts on d-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as d,l-threo-dihydrosphingosine, n,n-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol. The long form of sphingosine kinase 1, an N-terminal extension, is responsible for FceRI-mediated calcium mobilization and may play a role in other ligand mediated signaling events.
Additional Text
Gene Name
SPHK1
Gene ID
20698
Uniprot ID
Q8CI15
Application Notes
Blocking peptide for use with mouse Phospho sphingosine kinase 1 (Ser225) antibody (Cat. Nos. X1849P).
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations