Sphingosine Kinase 2, Long Form, Human

Catalogue Number: X1881B-EXA

Manufacturer:ExAlpha
Type:Blocking Peptides
Alias:Sphk2-L, N-terminal-extended Sphingosine Kinase 2
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen:
Application: Inh-Fun

Description

Description: Rat sphingosine kinase 1 catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (spp)(sphingosine + ATP = sphingosine 1-phosphate + ADP), a lipid mediator with both intra- and extracellular functions. also acts on d-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as d,l-threo-dihydrosphingosine, n,n-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol. The long form of sphingosine kinase 1, an N-terminal extension, is responsible for FceRI-mediated calcium mobilization and may play a role in other ligand mediated signaling events.

Additional Text

Gene ID

56848

Gene Name

SPHK2

Uniprot ID

Q9NRA0

Application Notes

Blocking peptide for use with Human Sphingosine Kinase 2, Long Form antibodies (Cat. No. X1775P & X1880P).

Storage Note

Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles