Serine Palmitoyltransferase 1
Catalogue Number: X2067B-EXA
| Manufacturer: | ExAlpha |
| Type: | Blocking Peptides |
| Alias: | Long chain base biosynthesis protein 1; LCB-1; LCB1; Serine-palmitoyl-CoA transferase 1; SPT1; SPT 1; SPT-1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Application: | WB, IHC, Blk |
Description
Description: Sphingolipids play essential roles in various cellular events, including proliferation, differentiation, senescence, apoptosis, and inflammatory responses. Serine palmitoyltransferase (SPT) is the initial and rate-limiting enzyme in the de novo sphingolipid biosynthesis, and thus regulates the level of sphingolipids in cells. Immunohistochemical study revealed widespread distribution of the enzyme with most strong expression in brain and digestive tract. Two subunits, SPT1 and SPT2 at a stoichiometry of 1:1, are involved in the enzymatic activity of SPT.
Additional Text
Gene Name
SPTLC1
Uniprot ID
O15269
Gene ID
10558
Application Notes
For use with serine palmitoyltransferase 1 polyclonal antibodies (Cat. No. X1862P & X2066P).
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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