Lass1 (Cross reacts with GDF1)
Catalogue Number: X2294B-NMB
| Manufacturer: | Nordic MuBio |
| Type: | Blocking Peptides |
| Alias: | LAG1 longevity assurance homolog 1, UOG-1 protein, LAG1, LASS1, LAG1 longevity assurance homolog 1 (LASS 1) |
| Shipping Condition: | RT |
| Unit(s): | 50 ug |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: | Synthetic peptide derived from the human Lass1 protein. |
| Application: | WB, Blk |
Description
Description: LAG1 is a longevity gene, the first such gene to be identified. Originally cloned from the yeast Saccharomyces cerevisiae. A close homolog of this gene, LAC1, has been found in the yeast genome. The human homolog of LAG1 has functions in human aging. LAG1 may be involved in neurodegenerative diseases and human aging. Lass1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. Located in the endoplasmic reticulum membrane; LAss1 is a multi-pass membrane protein.
Additional Text
Gene ID
10715
Gene Name
CERS1
Uniprot ID
P27544
Application Notes
For use with Lass1 polyclonal antibodies (Cat. No. X2084P & X2310P).
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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