Roundabout homolog 1, ROBO1
Catalogue Number: X2335B-EXA
| Manufacturer: | ExAlpha |
| Type: | Blocking Peptides |
| Alias: | H-Robo-1, Deleted in U twenty twenty |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | |
| Immunogen: | Synthetic peptide derived from human ROBO1 protein |
| Application: | WB |
Description
Description: Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development. Defects in ROBO1 may be a cause of breast and lung cancer. ROBO1 maps within a region of overlapping homozygous deletions characterized in both small cell lung cancer cell lines (SCLC) and in a breast cancer cell line.
Additional Text
Gene ID
6091
Gene Name
ROBO1
Uniprot ID
Q9Y6N7
Application Notes
For use with ROBO1 polyclonal antibodies (Cat. No. X2313P and X2334P).
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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