LNX1
Catalogue Number: X2341B-EXA
| Manufacturer: | ExAlpha |
| Type: | Blocking Peptides |
| Alias: | Numb-binding protein 1; Ligand of Numb-protein X 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | |
| Immunogen: | Synthetic peptide derived from the human LNX1 protein. |
| Application: | WB |
Description
Description: LNX1 is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65
Additional Text
Gene Name
LNX1
Gene ID
84708
Uniprot ID
Q8TBB1
Application Notes
For use with LNX1 polyclonal antibodies (Cat. No. X2316P & X2340P).
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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