Monocarboxylate Transport 2
Catalogue Number: X2372B-EXA
| Manufacturer: | ExAlpha |
| Type: | Blocking Peptides |
| Alias: | MCT2; Solute carrier family 16 member 7; SLC16A7 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | |
| Immunogen: | Peptide Immunogen |
| Application: | WB |
Description
Description: Functions as a proton-linked monocarboxylate transporter and catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a very high affinity pyruvate transporter. MCT2 is a cell membrane; Multi-pass membrane protein with high expression in testis, moderate to low expression in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocytes. The normal expression of MCT2 is restricted to low levels of expression in normal tissues, but is widely expressed in cancer cells.
Additional Text
Gene ID
9194
Gene Name
Slc16a7
Uniprot ID
O60669
Application Notes
For use with Monocarboxylate Transport 2 polyclonal antibodies (Cat. No. X2368P & X2371P).
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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