Sheep anti Human Glypican-3 (GPC3)
Catalogue Number: X2395P-EXA
| Manufacturer: | ExAlpha |
| Type: | Primary Antibody |
| Alias: | GPC3, GPC-3, OCI5, OCI-5, GTR2-2, MXR7 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ug |
| Host name: | Sheep |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | C terminal recombinant protein (~70aa) which does not overlap with clone 1G12 epitope) |
| Application: | IHC-P, WB, IHC |
Description
Description: Glypican-3 encodes a putative extracellular proteoglycan that is inferred to play an important role in growth control in embryonic mesodermal tissues in which it is selectively expressed. It appears to form a complex with insulin-like growth factor and hence modulate IGF2 action. Glypican-3 is the human homolog of OCI-5, a GPI-linked proteoglycan first isolated from rat intestine. Originally identified as the molecular basis for Simpson-Golabi-Behmel syndrome (SGBS) also called Simpson dysmorphia syndrome (SDYS).
Additional Text
Gene Name
GPC3
Gene ID
2719
Uniprot ID
P51654
Antibody Clonality
Polyclonal
Application Notes
Antibody can be used for immunohistochemistry on paraffin-embedded tissues (10 µg/ml) and Western blotting (5-10 µg/ml). Optimal concentration should be evaluated by serial dilutions.
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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