Sphingosine 1 Phosphate 4 Receptor (NT) (EDG6)
Catalogue Number: X2717B-NMB
| Manufacturer: | Nordic MuBio |
| Type: | Blocking Peptides |
| Shipping Condition: | RT |
| Unit(s): | 50 ug |
| Application: | NT, Blk |
Description
Description: This peptide is the immunogen used to make Cat # X1593P. S1P4/EDG6 polyclonal antibody. EDG6 (S1P4) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG6 (S1P4) is sphingosine 1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG6 (S1P4) is expressed in lymphoid and hematopoietic tissue and in the lungs. Blocking Peptide to Cat # X1593P.
Additional Text
Gene ID
8698
Gene Name
S1PR4
Uniprot ID
O95977
Application Notes
For use with S1P4 polyclonal antibody (Cat. No. X1593P). Optimal concentration should be evaluated by serial dilutions.
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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