Rabbit anti Human S100P-Binding Protein

Catalogue Number: X2757P-EXA

Manufacturer:ExAlpha
Type:Polyclonal Primary Antibody - Unconjugated
Alias:S100PBP
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide derived from human S100P-binding protein.
Application: WB, IHC, EIA

Description

Description: The function of this binding protein is not fully known. It is known to interact with the S100P and colocalizes with S100P in the nucleus. S100P may stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE). Expressed in brain, spleen, and lung. Not detected in pancreas or liver. In pancreas, expressed predominantly in islet cells and to a lesser extent in acinar cells, but not expressed in ductal cells. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. Detected in pancreatic ductal adenocarcinoma cells (at protein level). Not detected in non-neoplastic ductal epithelium (at protein level).

Additional Text

Gene ID

64766

Uniprot ID

Q96BU1

Purification

Affinity Purified

Gene Name

S100PBP

Antibody Clonality

Polyclonal

Application Notes

Optimal concentration should be evaluated by serial dilutions.

Storage Note

Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles