INDIGO Biosciences Receives Approval from California Water Boards for Use of Its Bioassays in Recycled Water Monitoring

INDIGO Biosciences Receives Approval from California Water Boards for Use of Its Bioassays in Recycled Water Monitoring

INDIGO’s Aryl Hydrocarbon Receptor (AhR) and Estrogen Receptor Alpha (ERα) Bioassays Approved for Monitoring Constituents of Emerging Concern Per Recycled Water Policy

State College, PA (November 7, 2022) – INDIGO Biosciences, Inc. has received approval from the California Water Boards, State Water Resources Control Board, for the use of two of its bioassays in recycled water monitoring. INDIGO has been approved for the use of its Aryl Hydrocarbon Receptor (AhR) and Estrogen Receptor Alpha (ERα) bioassays as bioanalytical screening tools for Constituents of Emerging Concern (CECs) in recycled water.

“Both of these assays were developed by INDIGO’s in-house scientific team,” said Fred Marroni, INDIGO’s President and CEO, “and this approval highlights INDIGO’s scientific expertise in developing screening tools that can help protect the environment and human health. We look forward to developing additional bioassays that can help water boards and regulators everywhere monitor for contaminants that pose potential environmental and health risks.”

As part of the approval process, INDIGO submitted validation packages for both its AhR and ERα assays. Both validation packages demonstrated the utility of the bioassays for use as biological screening tools for CECs as set forth in California’s Recycled Water Policy. These assays are useful in screening for biological activity due to CECs such as estradiol, bisphenol A, nonylphenol, dioxin-like chemicals, polycyclic aromatic hydrocarbons, and pesticides.

INDIGO’s bioassays are also effective in identifying the presence of CECs for which no relevant data is available, such as new compounds that may be entering the market or mixtures of compounds, which may occur in recycled water. The presence of these new compounds and mixtures can be missed by targeted analytical methods. This is important since compounds that interact with these receptors can adversely affect human health including reproductive and developmental issues and have been linked to various types of cancer.

About INDIGO Biosciences, Inc.

INDIGO Biosciences is a leading provider of cell-based luciferase reporter assays. Our products and services are used in a broad range of industries such as environmental, drug discovery, academia, and contract research organizations. INDIGO assays are available as turnkey kits for use by scientists, or INDIGO can perform the assays in our own lab as a service. INDIGO’s assays have been demonstrated to provide fast, accurate, reproducible results, and we are dedicated to supporting scientists through reliable science, easy-to-use products, and a highly qualified technical support team


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