Exalpha was founded over 20 years ago by a group of scientists dedicated to accelerating the pace of discovery in the life science arena by rapidly developing and marketing unique products at the forefront of science.

In order to develop great products, you have to ask the right questions when you start. Where some companies are satisfied with ‘average’, ‘good enough’ or ‘me too’ products, Exalpha only settles for products that answer the pertinent questions. Exalpha continually monitors scientific trends and recent literature, we strive to produce products that answer real needs. Exalpha has a long history of developing uniquely superior products that simply perform well, allowing researchers to focus on the task at hand and not on the quality of a supplier’s products.

Product Categories

Custom IgY Services

Custom IgY Services

Exalpha offers a complete set of custom services. These services include:

Want to perform your own custom chicken antibody purification?

We also offer IgY purification kits for you to perform the purification yourself.

Compared to the competition:

  • Our kit is cheaper to buy (per mg IgY purified)
  • The yield obtained is 50% higher than our major competitor

The antibody purification kit comes with detailed instructions. Furthermore, should you have problems with your kit, we provide technical support on the antibody purification protocol.


Code Name Product Type
IK 8000 EggsPress IgY Purification Kit (80 yolks) Kits
IK 500 EggsPress IgY Purification Kit (5 yolks) Kits
IK 4000 EggsPress IgY Purification Kit (40 yolks) Kits
IK 2000 EggsPress IgY Purification Kit (20 yolks) Kits
0Pre-immunization egg collectionIf requested
0Immunize chickens with 0.25 mg of antigen mixed with Complete Freund’s Adjuvant
10Immunize chickens with 0.15 mg of antigen mixed with Incomplete Freund’s Adjuvant
20Immunize chickens with 0.15 mg of antigen mixed with Incomplete Freund’s Adjuvant
30Immunize chickens with 0.15 mg of antigen mixed with Incomplete Freund’s Adjuvant
40-60Post-immune Egg collectionDepending on the chicken’s egg laying habits
Process Details
Antigen requirement0.7 mg per 1 chicken protocol for immunizations. We also require you to fill out our antigen form with antigen details. You can find our form by clicking on this link.
Average yield12-15 eggs per chicken
lgY yieldApproximately 60 mg/yolk
NotesYolk lgY isolation is available for nominal cost, and can be shipped in PBS containing 0.1% NaN3

We can also ship intact eggs

How much antigen should you ship us?

We recommend immunization with, between 0.5 and 2 milligrams of purified or recombinant protein per hen and prefer a concentration of at least 2 mg/ml. If possible, please supply us with 4 vials of immunogen (for 4 immunizations), the first vial (for the primary immunization) with twice as much antigen as the others.


For those customers requiring large scale production of IgY, we can meet your specific requirements. All laboratory work is performed using standard operating procedures to assure the highest quality of your custom product depending on your immunogen, how much IgY is required and over what time-frame, we will design a custom project that will suit your needs.

For bulk quantities of IgY, we usually recommend multiple hen immunizations and the pooling of their eggs for IgY purification.

Custom Services Projects

Option 1Option 2
DescriptionClient antigen to egg collectionClient Antigen to IgY Antibody
Client provides AntigenXX
Immunization of 1 chicken*XX
Whole eggs or egg yolks (10-20)XX
IgY purification (500mg to 750 mg of antibody fraction)X
Project Time10 to 12 weeks11-13 weeks
Project CostsClick here to inqure about pricing
Additional Services:
Pre-Immune IgY sample
Board per chicken after project is completed
Additional Boosts
Post-Immune IgY Purification.
*Should you need anti-Chicken secondary antibodies, then Exalpha Biologicals offers a full range. Please contact us for more details
**We are also able to commercialize this antibody for you in return for some free IgY. Please ask us for further details.

Improve your Flow Cytometry with FIX&PERM® Buffers and Recombinant Engineered Antibodies

Contact UsView All Products You have gone to great lengths to collect and suspend your cellular sample, and as antibody Read More...

SCICONS anti-dsRNA antibody in the fight against COVID-19

Contact Us View all products - COMING SOON! SCICONS’ mouse anti double-stranded RNA antibody (clone J2) was used in crucial Read More...

exalpha Resources

exalpha Resources

Contact UsView All Products CategoriesIgY OverviewProtocols IgY Overview What is IgY? IgY is an immunoglobulin first described in 1893 when Read More...