Developmental biology is the study of how organisms grow and develop. It is a very broad field that incorporates a number of interrelated research interests. Embryology studies the developmental events that occur during the generation of gametes, fertilization, organogenesis, and creation of the embryo and fetus. Stem cell biology examines how stem cells control self-renewal, lineage specification, fate commitment, and differentiation. Regenerative biology is focused primarily on tissue repair and regeneration and thus embraces many of the goals of stem cell biologists to understand how to drive terminally differentiated cells back into a progenitor state.

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Stem Cell Research

Stem cells are usually defined functionally by their ability to proliferate for an extended time and to differentiate from unspecialized cells into specific cell types. In addition, stem cell populations are identified by the expression, or lack of expression, of various markers. Listed below are antibodies from GeneTex’s stem cell catalog that are valuable tools for the characterization and isolation of stem cells. The tables list representative markers for embryonic, neural, hematopoietic, and mesenchymal stem cell populations and appropriate reagents to detect these factors (1,2).

Marker Antibody
Oct4 (POU5F1) GTX627419
Nanog GTX627421
Sox2 GTX627404
SSEA-4 GTX48037
CD30 GTX01872
GATA4 GTX113194
CD133 GTX100567
Marker Antibody
Vimentin GTX629744
NeuroD1 GTX134069
MAP2 GTX133109
Tau GTX130462
Synaptophysin GTX633972
OTX2 GTX133210
GFAP GTX108711
Marker Antibody
CD73 GTX113509
CD90 / Thy1 GTX130072
CD105 GTX112685
Fibronectin GTX112794
N-Cadherin GTX127345


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