Cytokine Storm & Pyrotosis Antibodies

SARS-CoV-2 / COVI D-19 pathogenesis is inextricably linked to immune system dysfunction. Hypercytokinemia (or “cytokine storm” ) is a hyperinflammatory response that can lead to acute respiratory distress syndrome (ARDS} and other systemic complications in COVI D-19 patients.

CXCL8 / IL8 antibody

Ill beta antibody

IL6 antibody

Cat. No .Product NameClonalityReactivityApplications
GTX10026C Reactive Prot ein antibody [Cl]Ms mAbHuWB, ELISA, IH C, Pu rifi cati on, Turbidim etry
GTX01262C Reactive Protein antibody [N1C3]Rb pAbHu, RatWB, IH C
GTX31176CXCll 0 / IPlO antibodyRb pAbHuWB, IHC-P, ELISA, Neutr alizin g/ Block ing
GTX115959CXCL8 / IL8 antibodyRb pAbHuWB, IH C-P, FACS
GTX01155CXCR3 antibody [JA61-33]Rb mAbHuWB, ICC/ IF
GTX108145CXCR3 antibody [Nl], N-termRb pAbHuWB, IH C-P
GTX60943D-Dim er antibody [28 ]Ms mAbHu, DogWB, ELISA
GTX101005 FGFlO antibodyRb pAbHu, RatWB
GTX101007 FGF12 antibodyRb pAb MsWB
GTX101008 FGF13 antibodyRb pAbHu, Ms, RatWB, IH C-P
GTX130346 FGF1 4 antibodyRb pAbHuWB, ICC/ IF
GTX128496 FGF1 8 antibodyRb pAbHuWB
GTX01054 FGF21 antibody [JAl0-97]Rb mAbHu, Ms, RatWB, IH C-P
GTX111877 FGF21 antibody [N3C3]Rb pAbHuWB, ICC/ IF, IH C-P
GTX31157 G-CSF antibodyRb pAbHuWB, IH C-P, ELISA, Neutralizing/Blocking
GTX59748 GM-CSF antibodyRb pAbHuWB, Neutralizing/Blocking
GTX129003 HGF (alpha subunit) antibodyRb pAbHuWB
GTX111810 HGF antibodyRb pAbHuWB
GTX74034 Ill beta antibodyRb pAbHu, Ms, RatWB, ICC/ IF, IHC-P, IHC-Fr, ELISA, Fu nctional Assay, IHC
GTX634188Ill beta antibody [GT289]Ms mAbHuWB, ICC/ IF
GTX130513lll0 antibodyRb pAbHu, MsWB, IH C-Fr, ELISA
GTX632359lll0 antibody [GTS5111]Ms mAbHu, Ms, RatWB, IH C-P
GTX32675IL-1 8 antibodyRb pAbHu, MsWB, IP
GTX110527IL6 antibodyRb pAbHu, MsWB, IH C-P, IHC-Fr
GTX131448IL7 antibodyRb pAbHuWB
GTX51537IL9 antibodyRb pAbMs, RatWB, IH C-P
GTX15624Interferon gamma antibody [2G1]Ms mAbHu, MsWB, ELISA, sELISA
GTX101416LDH A antibodyRb pAbHu, Ms, RatWB, ICC/ IF, IH C-P
GTX101747LDH-B antibodyRb pAbHu, Ms, RatWB, ICC/ IF, IH C-P
GTX110520TNF alpha antibodyRb pAbHu, Ms, Rat, BovWB, ICC/ IF, IH C-P
GTX102643VEGF antibodyRb pAbHu, Ms, RatWB, IH C-P
GTX21316VEGF antibody [VGl]Ms mAbHu, Ms, RatWB, ICC/ IF, IH C-P, IHC-Fr, ELISA

LDH-B antibody

TNF alpha antibody

VEGF antibody


Pyroptosis is a programmed cell death process executed by inflammatory caspases upon initiation of canonical or non-canonical mechanisms. It is triggered by specific inflammatory caspases (caspase-1,-4,-5,-11} that are distinct from those responsible for apoptosis. Both the canonical and non-canonical pathways lead to the activation of gasdermin D (GSDMD}, which forms pores that cause cellular leakage and lysis. The resultant extracellular release of cytoplasmic components unleashes a local inflammatory cascade that can become systemic, underscoring the importance of pyroptosis’ normal function in mobilizing immune cells against pathogens. Nevertheless, pyroptosis can also contribute to inflammation-related pathology, including cancer progression and autoimmune disease.

Caspase 1 antibody [N1N3]

Gasdermin D antibody [N1N3]

NLRP3 antibody

Cat. No .Product NameClonalityReactivityApplications
GTX116487AIM2 antibodyRb pAbHuWB
GTX102366CARD12 antibody [Nl], N-termRb pAbHuWB
GTX133447Caspase 1 (cleaved Asp297) antibodyRb pAbHuWB
GTX14367Caspase 1 antibody [14F468]Ms mAbHu, Ms, RatWB, ICC/IF, IHC-P
GTX101322Caspase 1 antibody [N1N3]Rb pAbHuWB, ICC/IF, IHC-P
GTX123675Caspase 1 p10 subunit antibodyRb pAbHu, Ms, RatIHC-P
GTX134551Caspase 1 p10 subunit antibodyRb pAbHu, Ms, RatWB, IHC-P
GTX11701Caspase 1 p20 subunit antibodyRb pAbMs, RatWB
GTX10454caspase 11 antibody [17D9]Rb pAbMsWB, IHC-Fr, IP
GTX134552caspase 4 antibodyRb pAbHu, Ms, RatWB, IHC-P
GTX113639caspase 4 antibodyRb pAbHuWB, IHC-P
GTX31701caspase 5 antibodyRb pAbHu, MsWB, IHC-P
GTX116840Gasdermin D antibody [N1N3]Rb pAbHuWB
GTX74034IL1 beta antibodyRb pAbHu, Ms, RatWB, ICC/IF, IHC-P, IHC-Fr, ELISA, Functional Assay, IHC
GTX634188IL1 beta antibody [GT289]Ms mAbHuWB, ICC/IF
GTX32675IL-18 antibodyRb pAbHu, MsWB, IP
GTX22549NAIP antibodyRb pAbHuWB
GTX108216NEK7 antibody [C2C3], C-termRb pAbHu, MsWB, ICC/IF, IHC-P
GTX101150NFkB plO0 antibody [C2C3], C-termRb pAbHu, MsWB, IP
GTX110585NFkB p105 antibodyRb pAbHu, MsWB, ICC/IF, IHC-P, Ch IP assay, IHC
GTX107678NFkB p65 antibodyRb pAbHu, Ms, RatWB, ICC/IF, IHC-P, IP, EMSA
GTX133569NLRP3 antibodyRb pAbHu, MsWB
GTX16827P2X7 antibodyRb pAbHu, Ms, RatWB, ICC/IF, IHC-Fr, FACS, LCI
GTX31510Pannexin 1 antibodyRb pAbHu, Ms, RatWB, IHC-P, ELISA
GTX102474TMSl antibody [N1C3]Rb pAbHuWB, ICC/IF, IHC-Fr

TMSl antibody [N1C3]

NFkB p65 antibody

Caspase 4 antibody


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