Cytokine Storm & Pyrotosis Antibodies

SARS-CoV-2 / COVI D-19 pathogenesis is inextricably linked to immune system dysfunction. Hypercytokinemia (or “cytokine storm” ) is a hyperinflammatory response that can lead to acute respiratory distress syndrome (ARDS} and other systemic complications in COVI D-19 patients.

CXCL8 / IL8 antibody
(GTX115959)

Ill beta antibody
(GTX74034)

IL6 antibody
(GTX110527)

Cat. No .	Product Name	Clonality	Reactivity	Applications
GTX10026	C Reactive Prot ein antibody [Cl]	Ms mAb	Hu	WB, ELISA, IH C, Pu rifi cati on, Turbidim etry
GTX01262	C Reactive Protein antibody [N1C3]	Rb pAb	Hu, Rat	WB, IH C
GTX31176	CXCll 0 / IPlO antibody	Rb pAb	Hu	WB, IHC-P, ELISA, Neutr alizin g/ Block ing
GTX115959	CXCL8 / IL8 antibody	Rb pAb	Hu	WB, IH C-P, FACS
GTX01155	CXCR3 antibody [JA61-33]	Rb mAb	Hu	WB, ICC/ IF
GTX108145	CXCR3 antibody [Nl], N-term	Rb pAb	Hu	WB, IH C-P
GTX60943	D-Dim er antibody [28 ]	Ms mAb	Hu, Dog	WB, ELISA
GTX101005	FGFlO antibody	Rb pAb	Hu, Rat	WB
GTX101007	FGF12 antibody	Rb pAb	Ms	WB
GTX101008	FGF13 antibody	Rb pAb	Hu, Ms, Rat	WB, IH C-P
GTX130346	FGF1 4 antibody	Rb pAb	Hu	WB, ICC/ IF
GTX128496	FGF1 8 antibody	Rb pAb	Hu	WB
GTX01054	FGF21 antibody [JAl0-97]	Rb mAb	Hu, Ms, Rat	WB, IH C-P
GTX111877	FGF21 antibody [N3C3]	Rb pAb	Hu	WB, ICC/ IF, IH C-P
GTX31157	G-CSF antibody	Rb pAb	Hu	WB, IH C-P, ELISA, Neutralizing/Blocking
GTX59748	GM-CSF antibody	Rb pAb	Hu	WB, Neutralizing/Blocking
GTX129003	HGF (alpha subunit) antibody	Rb pAb	Hu	WB
GTX111810	HGF antibody	Rb pAb	Hu	WB
GTX74034	Ill beta antibody	Rb pAb	Hu, Ms, Rat	WB, ICC/ IF, IHC-P, IHC-Fr, ELISA, Fu nctional Assay, IHC
GTX634188	Ill beta antibody [GT289]	Ms mAb	Hu	WB, ICC/ IF
GTX130513	lll0 antibody	Rb pAb	Hu, Ms	WB, IH C-Fr, ELISA
GTX632359	lll0 antibody [GTS5111]	Ms mAb	Hu, Ms, Rat	WB, IH C-P
GTX32675	IL-1 8 antibody	Rb pAb	Hu, Ms	WB, IP
GTX110527	IL6 antibody	Rb pAb	Hu, Ms	WB, IH C-P, IHC-Fr
GTX131448	IL7 antibody	Rb pAb	Hu	WB
GTX51537	IL9 antibody	Rb pAb	Ms, Rat	WB, IH C-P
GTX15624	Interferon gamma antibody [2G1]	Ms mAb	Hu, Ms	WB, ELISA, sELISA
GTX101416	LDH A antibody	Rb pAb	Hu, Ms, Rat	WB, ICC/ IF, IH C-P
GTX101747	LDH-B antibody	Rb pAb	Hu, Ms, Rat	WB, ICC/ IF, IH C-P
GTX110520	TNF alpha antibody	Rb pAb	Hu, Ms, Rat, Bov	WB, ICC/ IF, IH C-P
GTX102643	VEGF antibody	Rb pAb	Hu, Ms, Rat	WB, IH C-P
GTX21316	VEGF antibody [VGl]	Ms mAb	Hu, Ms, Rat	WB, ICC/ IF, IH C-P, IHC-Fr, ELISA

LDH-B antibody
(GTX101747)

TNF alpha antibody
(GTX110520)

VEGF antibody
(GTX102643)

Pyroptosis

Pyroptosis is a programmed cell death process executed by inflammatory caspases upon initiation of canonical or non-canonical mechanisms. It is triggered by specific inflammatory caspases (caspase-1,-4,-5,-11} that are distinct from those responsible for apoptosis. Both the canonical and non-canonical pathways lead to the activation of gasdermin D (GSDMD}, which forms pores that cause cellular leakage and lysis. The resultant extracellular release of cytoplasmic components unleashes a local inflammatory cascade that can become systemic, underscoring the importance of pyroptosis’ normal function in mobilizing immune cells against pathogens. Nevertheless, pyroptosis can also contribute to inflammation-related pathology, including cancer progression and autoimmune disease.

Caspase 1 antibody [N1N3]
(GTX101322)

Gasdermin D antibody [N1N3]
(GTX116840)

NLRP3 antibody
(GTX133569)

Cat. No .	Product Name	Clonality	Reactivity	Applications
GTX116487	AIM2 antibody	Rb pAb	Hu	WB
GTX102366	CARD12 antibody [Nl], N-term	Rb pAb	Hu	WB
GTX133447	Caspase 1 (cleaved Asp297) antibody	Rb pAb	Hu	WB
GTX14367	Caspase 1 antibody [14F468]	Ms mAb	Hu, Ms, Rat	WB, ICC/IF, IHC-P
GTX101322	Caspase 1 antibody [N1N3]	Rb pAb	Hu	WB, ICC/IF, IHC-P
GTX123675	Caspase 1 p10 subunit antibody	Rb pAb	Hu, Ms, Rat	IHC-P
GTX134551	Caspase 1 p10 subunit antibody	Rb pAb	Hu, Ms, Rat	WB, IHC-P
GTX11701	Caspase 1 p20 subunit antibody	Rb pAb	Ms, Rat	WB
GTX10454	caspase 11 antibody [17D9]	Rb pAb	Ms	WB, IHC-Fr, IP
GTX134552	caspase 4 antibody	Rb pAb	Hu, Ms, Rat	WB, IHC-P
GTX113639	caspase 4 antibody	Rb pAb	Hu	WB, IHC-P
GTX31701	caspase 5 antibody	Rb pAb	Hu, Ms	WB, IHC-P
GTX116840	Gasdermin D antibody [N1N3]	Rb pAb	Hu	WB
GTX74034	IL1 beta antibody	Rb pAb	Hu, Ms, Rat	WB, ICC/IF, IHC-P, IHC-Fr, ELISA, Functional Assay, IHC
GTX634188	IL1 beta antibody [GT289]	Ms mAb	Hu	WB, ICC/IF
GTX32675	IL-18 antibody	Rb pAb	Hu, Ms	WB, IP
GTX22549	NAIP antibody	Rb pAb	Hu	WB
GTX108216	NEK7 antibody [C2C3], C-term	Rb pAb	Hu, Ms	WB, ICC/IF, IHC-P
GTX101150	NFkB plO0 antibody [C2C3], C-term	Rb pAb	Hu, Ms	WB, IP
GTX110585	NFkB p105 antibody	Rb pAb	Hu, Ms	WB, ICC/IF, IHC-P, Ch IP assay, IHC
GTX107678	NFkB p65 antibody	Rb pAb	Hu, Ms, Rat	WB, ICC/IF, IHC-P, IP, EMSA
GTX133569	NLRP3 antibody	Rb pAb	Hu, Ms	WB
GTX16827	P2X7 antibody	Rb pAb	Hu, Ms, Rat	WB, ICC/IF, IHC-Fr, FACS, LCI
GTX31510	Pannexin 1 antibody	Rb pAb	Hu, Ms, Rat	WB, IHC-P, ELISA
GTX102474	TMSl antibody [N1C3]	Rb pAb	Hu	WB, ICC/IF, IHC-Fr