As the inventor of spin column based protein extraction and cell fractionation technologies, Invent Biotechnologies offers disruptive solutions for scientists around the world that simplify, accelerate, and improve their scientific endeavors. Our proprietary processes and formulations are revolutionary and have fundamentally changed how protein samples are prepared. With years of research and development, we have discovered the fastest, easiest, and most reliable ways for protein extraction and cell fractionation.


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Spin-column-based protein extraction / cell fractionation – a big leap for protein research

For the first time ever, the tasks that used to be tedious, lengthy, and unpredictable can now be performed by just a couple of quick spins using a tabletop centrifuge, delivering unsurpassed speed, convenience, consistency, and accuracy by eliminating uncontrollable variables associated with traditional solution-based procedures.

Invent Biotechnologies is the inventor of spin column-based protein extraction and cell fractionation. They successfully developed the Minute™ series of protein extraction and sub-cellular fractionation products.

The Minute™ Benefits:

  • Super-fast (as quick as 1 minute)
  • Small sample size
  • Complete profile
  • Unaltered endogenous baseline
  • All living organism and tissue types

The Minute™ Applications:

  • Protein trafficking/translocation
  • Protein-protein interaction
  • Protein modification
  • Signal transduction
  • Daily protein analysis

Overview of the procedure

Advantages of Minute Protein Extraction

Minute™ Protein Extraction is the world’s fastest and most reliable method for protein sample preparation:

Minute™Traditional Methods
Solution-basedNoYes
Process timeAs quick as 1 minute30 minutes – 1 hour
Complete protein profilePreservedAltered
Spin column formatYesNo
Suitability for comparative studyYesNo
Protein lossMinimal and proportionallyNon-proportionally

Minute™ Cell Fractionation Kits utilize spin-column-based technology to eliminate unwanted variables associated with traditional homogenizer and density gradient centrifugation/ultracentrifugation:

Minute™Traditional Methods
HomogenizerNoYes
UltracentrifugationNoYes
Process timeMinutes – 2 hoursHours to days
Sample sizeSmallLarge
Spin column filterYesNo
ConsistencyExcellentPoor
Cross contaminationLowHigh

Product offering

MinuteTM kits are available for

  • Rapid protein extraction, e.g. Total Protein Extraction Kit
  • Subcellular structure fractionation, e.g. Cytoplasmic and Nuclear Extraction Kit for Cells

Tips for Detecting

Phosphoproteins by Western Blot

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Radio-immunoprecipitation assay buffer

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A Tough Challenge

Protein Extraction from Adipose Tissues

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Solution-based vs. Spin Column-Based Technologies

Technical Breakthrough for Protein Sample Preparation

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How to Choose Membrane Protein Isolation Kits

Plasma Membrane Isolation Kit

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