SBI is a small biotech company that’s delivered innovative products and services for molecular and cell biology research since January 2004, when they sold their first lentivectors and pPACK lentivirus packaging systems.

They focus on being the first company to bring the most recent methodologies to market—they were the first company to deliver exosome research reagents and CRISPR/Cas9 vectors—so researchers could quickly take advantage of the latest, most powerful approaches.

Dedicated to quality, many of their products and most of their service offerings are completed in their state-of-the-art facility in Palo Alto CA, enabling them to maintain control over manufacturing conditions and quality, ensure their service projects remain confidential and deliver frequent and timely service project status updates.

Their experienced staff includes a high proportion of PhD-level scientists who interact directly with customers to provide product and services support.


Product Categories

Supporting all aspects of your exosome research, SBI’s products enable quantitative, high-throughput, and high quality studies and deliver unparalleled capabilities

Get everything you need for studying and using exosomes, from isolation and characterization, to cargo profiling and engineering, and more. Whatever methods you choose—whether you use ExoQuick or density gradient ultracentrifugation, want qPCR-based exosomal miRNA profiling or RNA-Seq methods—we’ve got the high-quality exosome research products to support your science and advance your work.

Exosome Labeling Kits & Products

Exosome Isolation Kits & Products

Exosome Detection Products

Exosome Engineering & Design Products

Pairing flexibility and choice with experienced scientific support, our wide range of CRISPR/Cas9 products put the power of genome engineering into your hands

Ready to use CRISPR/Cas9? Then SBI’s ready for you. With a comprehensive selection of CRISPR/Cas9 products for genome engineering—including Cas9 and gRNA delivery systems in a flexible range of formats, homologous recombination donor vectors, and AAVS1 Safe Harbor targeting—we can bring your genome engineering projects to life. Even better, our experienced technical support team is available to answer your questions on vector design, experimental setup, and more—just use the Contact page to start the conversation.

Widely regarded in the industry for delivering high-quality, high titer lentivirus preparations, SBI’s Lentivirus Production Products power cutting edge research across a range of applications

Whatever type of cell you’re trying to transduce, from 293T cells to the more difficult types like T cells and B cells, quality matters. Which is why SBI offers optimized virus packaging systems and reagents that can help you reliably obtain high titer preparations and efficient transfection and transduction.

Offering integrating and non-integrating vectors in viral and non-viral systems, SBI offers a wealth of options for gene delivery and expression

With a wealth of options for gene delivery and expression, SBI has the gene expression vectors to support a wide variety of projects. We offer viral and non-viral systems that can integrate into the genome or remain episomal as well as inducible systems for highly controlled expression. Not quite sure what you need? Contact one of our technical support scientists—use the form on the Contact page to get the conversation started.

Delivering unparalleled insight into the cell, SBI’s wide range of Imaging & Reporter Vectors provide ready-built, ready-to-use constructs for today’s busy labs

Gain clearer insight into the inner workings of the cell with one or more of SBI’s many Imaging & Reporter Vectors. Visualize subcellular compartments and track physiological processes such as differentiation, signal transduction, apoptosis, and more with our robust, reliable constructs.

From profiling to overexpression for biomarker discovery, basic and translational research, and more, SBI’s got the long and short of non-coding RNA covered

No matter the application, whether you’re checking individual miRNA or lncRNA expression levels or profiling a range of constructs, knocking-down or overexpressing miRNAs, SBI’s got your miRNA research and lncRNA research tools covered. Select from a wide-range of pre-made expression or knockdown constructs, or use one of our expertly curated profiling arrays.

Services

For comprehensive, end-to-end exosome services that include expert technical and data interpretation support from a highly experienced team, you can rely on SBI

CRISPR/Cas9 Services
SBI’s CRISPR/Cas9 Services can cover all or just part of your entire genome engineering workflow

  • CRISPR/Cas9 gRNA and HR Donor Cloning
  • CRISPR/Cas9 Cell Line Engineering

Minicircle Services
Get sustained transgene expression free from foreign DNA

RNA Services
SBI’s services team is ready to support your RNA studies

  • mRNA Synthesis Services
  • miRNA & lncRNA Profiling Services
  • Custom miRNA Precursor and anti-miRNA (miRZip) Services

Syn2Clone Custom Constructs
Affordable and easy custom plasmid construction

Exosome Services
Comprehensive, end-to-end exosome services

  • Exo-NGS
  • Exosome Proteomics Services
  • Exosome Lipidomics & Metabolomics Services
  • NTA-based Exosome Characterization
  • Exosome Isolation & Manufacturing
  • Exosome Engineering

Lentivirus Packaging
Get high-titer, transduction-ready lentivirus in as little as ten days

Stable Cell Lines
Get custom reporter, overexpression, or other type of cell line fast and hassle-free

  • Custom Overexpression Stable Cell Lines
  • Custom Luciferase-labeled Stable Cell Lines
  • Reporter Cell Lines

Simultaneous Detection of cfDNA and Exosomal Biomarkers

Expanding biomarker research capabilities Accelerate and enhance your biomarker discovery and characterization studies with the XCF™ COMPLETE Exosome & cfDNA Read More…

CRISPR/Cas9

Genome Engineering Tools from Novabiotein Cas9 (CRISPR associated protein 9) is an RNA-guided DNA endonuclease enzyme associated with the CRISPR Read More…

Stem Cell

Frequently Asked Questions (FAQs) Q: What method of reprogramming source cells is the most efficient? A: The retroviral method of Read More…

MicroRNA

Frequently Asked Questions (FAQs) MicroRNA profiling Q: How should I prepare or purify my RNA prior to QuantiMir cDNA synthesis? Read More…

Exoquick

ExoQuick Frequently Asked Questions (FAQs) Q: How do I decide which ExoQuick product to start with? ExoQuick or ExoQuick-TC?? A: Read More…

Exosomes Explained

How to use Exosomes

Exosomes Tools, from isolation to engineering Exosomes – extracellular vesicles (EVs) 30 – 200 nm in size were once thought Read More…

How Lentivirus Delivery Works

The pseudoviral particles can infect target cells and express genes, shRNAs, microRNAs and reporter molecules but cannot replicate within the Read More…

Exo-Fect™ Exosome Transfection

Exo-Fect is a novel nucleic acid transfer agent that enables the transfection of nucleic acids directly into isolated exosomes. The Read More…

PinPoint Targeted Integration System

The PinPoint Targeted Integration system allows users to easily and efficiently create isogenic stable cell lines in mammalian and other Read More…

Minicircle DNA Vector Technology

The Minicircle advantage Minicircles are episomal DNA vectors that are produced as circular expression cassettes devoid of any bacterial plasmid Read More…

PureFection™ Transfection Reagent

  PureFection™ Nanotechnology-based Transfection Reagent Deliver more DNA and siRNAs to cells than the leading lipid-based transfection kits PureFection is Read More…

Exosome Research Tools

  Comprehensive Toolset ExoQuick Isolation Exo-FBS media Antibodies and ELISAs Exo-RNA Purification Exo-RNA Next-Gen Sequencing Why are exosomes important? Once Read More…

MicroRNA Research

  Everything you need for microRNA research Integrated solutions for microRNA analysis SBI has developed innovative technologies and tools for Read More…

Cold Fusion Cloning Kit

The Cold Fusion technology is a simple, rapid and highly efficient cloning kit. It allows you to directly clone any Read More…

Exosome Antibodies, Arrays and ELISA Kits Detect and quantitate isolated exosomes

  Track and Quantitate Exosomes with Antibodies and ELISAs Exosomes are small membrane vesicles secreted by most cell types in Read More…

Sample Preperation

Overview Good sample preparation is arguably the most critical step in any analytical process because most techniques are unable to Read More…

Analysis of PCR

Overview Analysing and visualising your results is often the culmination of weeks if not months of work and can be Read More…

Genetic Engineering – Master the Essentials

Overview In Molecular Biology, the ability to successfully manipulate DNA is essential.  Stratech offers cutting edge cloning systems, genome editing Read More…

Visualisation

  Overview There are many ways of visualising your results; some of them more visual than others! Stratech supply sensitive Read More…

phiC31 Integrase Vector System One-step Gene Addition Technology

NEW from System Biosciences (SBI) the phiC31 Integrase Cloning system for mammalian genome engineering applications. This system provides the researcher Read More…