The conventional approach to commercial antibody production has improved remarkably since its inception well over 40 years ago. The development of reliable antibody reagents remains an essential goal in the quest to advance science and medicine. On the forefront of high-quality antibody manufacturing, GeneTex has solidified its position in the research community and the biotechnology industry.


GeneTex

 

Product Categories

  • Primary Antibodies
  • Antibody Panels
  • ELISA Antibody Pairs & Kits
  • Isotype Controls
  • Proteins & Peptides
  • Slides
  • Lysates
  • Serums & Plasmas
  • Reagents
  • Research Kits
  • Research Tools

Research Areas

  • Cancer
  • Neuroscience
  • Cell Biology
  • Metabolism
  • Epigenetics
  • Immunology
  • Development
  • Cell Markers
  • Signalling Pathways
  • Infectious Diseases
  • Zebrafish
  • Loading Controls

Neuroscience Literature

Amyotrophic Lateral Sclerosis (ALS) flyer Ion Channel flyer Neural Markers flyer Neurites and Synapses flyer
Neurodegenerative disorders flyer Neuropeptides flyer Neurotransmission flyer Vision and Retina flyer

Cancer Research Literature

Cancer Stem Cell flyer DNA Damage and Repair flyer Epithelial Mesenchymal Transition (EMT) flyer EGFR signaling flyer
Hypoxia Markers flyer Immune Checkpoints flyer VEGF_ANG Pathway flyer

 

Apoptosis
Autophagy
Cell Death
mTOR Signaling Pathway
Post Translational Modifications
Epitope Tag Antibodies
Flavivirus
Five Pillars of Ab V
Cell Cycle
Endothelial Cell Markers
Mitochondria
RNA-binding Proteins
Neural Markers
Exosome Microvesicle Markers

Quality

With a 20-year history of quality results, GeneTex sets itself apart from other antibody companies by taking the necessary steps to properly validate our antibodies. Antibody validation remains an industry-wide challenge with ramifications that can impact progress in the life sciences and medicine.

At GeneTex, product reliability is our primary concern. Stringent validation protocols have been established to test our antibodies for various applications, including WB, IP, IHC, IFA, FACS, and ELISA, using cell lines with known target protein expression levels and a diverse array of tissue samples. We know the importance of replicating results, so quality consistency between lots is maintained confidently through a combination of pre-qualified individual lots, dominant clones, and thorough quality control.

Founded by scientists, for scientists, we at GeneTex understand that researchers expect and demand product performance and fidelity. With GeneTex’s Knockout/Knockdown validation project, we’re committed to demonstrating to our customers that the products they are purchasing are completely reliable, every single time.

Our Commitment

There has been growing distrust of commercially available antibodies with regard to specificity and performance variability. As a result, the research community has demanded that antibody suppliers increase their efforts to more thoroughly validate their products. One approach to address this is through knockout or knockdown of the target protein.

At GeneTex, we continue to provide the research community with the highest quality and most stringently validated antibodies by utilizing CRISPR/Cas9- and shRNA-generated cell lysates for our western blot assays. To date, we have evaluated most of our featured products and will continue to expand these efforts throughout our entire antibody catalogue.

GeneTex

GeneTex primary antibodies have been tested through the use of various analytic strategies to ensure persistent quality and confirm antibody specificity. Based on the guidelines described by the International Working Group on Antibody Validation (IWGAV), GeneTex has been employing multiple approaches to certify antibody performance in our quality assurance process.

 

See GeneTex’s Validation Methods
GeneTex understands the absolute necessity for reliable antibodies to achieve accurate and reproducible experimental results. To optimize the performance of our reagents, we employ various analytic validation strategies to ensure both consistent quality (see GeneTex’s Approach to Antibody Lot-to-Lot Variability) and specificity. These modalities are in line with guidelines described by the International Working Group on Antibody Validation (IWGAV) and have become fundamental components of our quality assurance process:GeneTex

Polyclonal Antibodies

Polyclonal antibodies generated by an immunized animal consist of a heterogeneous mix of immunoglobulins derived from many B-cells that individually target distinct epitopes on an antigen. Often representing up to 5% of the total immunoglobulin, these antibodies are generally purified from the immune sera using antigen-affinity chromatography. Polyclonal antibodies are particularly useful for detecting proteins that are expressed at lower levels, and their performance is impacted to a lesser degree by alterations in the antigen (e.g., denaturation). GeneTex offers an extensive catalog of affinity-purified polyclonal antibodies directed against almost all key targets/proteins in the spectrum of biomedical research.

GeneTex

Monoclonal Antibodies

Monoclonal antibodies are produced by immortal hybridoma cells created from the fusion of antibody-producing splenic B-cells and myeloma cells, or by recombinant protein expression in mammalian cells. These antibodies have monovalent affinity and bind to a single epitope on the antigen. Purification is commonly accomplished through Protein A/G/L affinity chromatography.

GeneTex offers a broad selection of monoclonal antibodies directed against the majority of key targets/proteins in the spectrum of biomedical research.

GeneTex

fluorescence staining gift

FREE fluorescence Antibodies

Until September 30th only! Enjoy Fluorescence gifts with the purchase of 2 antibodies. Receive a complimentary fluorescence staining gift of Read More…

Five Pillars of Antibody Validation

GeneTex understands the absolute necessity for reliable antibodies to achieve accurate and reproducible experimental results. To optimize the performance of Read More…

GeneTex’s KO/KD-Validated QKI Antibodies for Neuroscience Research

QUAKING/QKI belongs to the STAR (Signal Transducer and Activator of RNA) family of RNA-binding proteins and functions in the differentiation Read More…