Nucleosomes
Recombinant Nucleosomes
SNAP-ChIP® spike-ins
dCypher® Nucleosome Panels
EpiDyne® Chromatin Remodeling Substrates
Modified Designer Nucleosomes (dNucs™)
Recombinant Nucleosomes (rNucs)
Oncogenic Nucleosomes (oncoNucs)
Variant Nucleosomes (vNucs)
Methyl DNA Designer Nucleosomes
Purified Nucleosomes (HeLa, Avian)
Nucleosome Components and Subunits
EpiCypher offers cutting edge tools and service for epigenetics and chromatin biology research. We pioneered the manufacture of designer recombinant nucleosomes that contain defined post-translational modifications. Our latest product, SNAP-ChIP, is the gold standard for antibody validation for chromatin IP, and also serves as the most reproducible spike-in for normalizing ChIP and ChIP-seq assays. EpiCypher also develops assays for chromatin-modifying enzymes and PTM-binding proteins using a variety of readouts, such as Alpha, FRET and radioactivity, employing nucleosome or peptide-based substrates.