EpiCypher offers cutting edge tools and service for epigenetics and chromatin biology research. We pioneered the manufacture of designer recombinant nucleosomes that contain defined post-translational modifications. Our latest product, SNAP-ChIP, is the gold standard for antibody validation for chromatin IP, and also serves as the most reproducible spike-in for normalizing ChIP and ChIP-seq assays. EpiCypher also develops assays for chromatin-modifying enzymes and PTM-binding proteins using a variety of readouts, such as Alpha, FRET and radioactivity, employing nucleosome or peptide-based substrates.

Product Categories

Recombinant Nucleosomes
SNAP-ChIP® spike-ins
dCypher® Nucleosome Panels
EpiDyne® Chromatin Remodeling Substrates
Modified Designer Nucleosomes (dNucs™)
Recombinant Nucleosomes (rNucs)
Oncogenic Nucleosomes (oncoNucs)
Variant Nucleosomes (vNucs)
Methyl DNA Designer Nucleosomes
Purified Nucleosomes (HeLa, Avian)
Nucleosome Components and Subunits

Epigenetics Reagents & Assays
SNAP-ChIP Certified Antibodies
PTM specific Antibodies
Cell Extracts
Histone Expression Vector

Recombinant Proteins
EpiDyne® Chromatin Remodeling Enzymes
Recombinant Histones
Histone Binding Domains
Modifying Enzymes

Histone Peptides & Arrays
Histone Peptide Arrays
H2A Peptides
H2B Peptides
H3 Peptides
H4 Peptides