Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies.

They have developed over 11,000 primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies.

In addition to reliable loading control and tag antibodies, their catalog includes over 1000 specific antibodies recognising proteins with phosphorylation, acetylation, or methylation modifications.

Their company promises fast delivery with strong, top quality scientific support.

Bioss Inc is located in the greater Boston area of Massachusetts, the centre of the world's largest and fastest growing biotech community.

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Bioss offers over 11,000 different primary antibodies. A primary antibody is an immunoglobulin that binds specifically to a particular protein or molecule of interest for the purpose of purifying or detecting and measuring it. We offer both polyclonal and monoclonal antibodies raised in rabbit, mouse, and goat. Polyclonal antibodies are able to recognize multiple epitopes on and antigen, making them more tolerant of minor changes in the antigen sequence. Monoclonal antibodies are made to be specific to a single epitope and can provide a stable long term supply when produced by hybridomas in vitro. Our primary antibodies are also made available conjugated to various fluorescent dyes, HRP, or Biotin.


Secondary Antibodies are used for indirect detection of target antigens. Bioss offers a wide variety of both conjugated and unconjugated secondary antibodies that can be used for fluorescent, colorimetric, and chemiluminescent detection of primary antibody in a wide range of applications. Using a secondary antibody provides increased sensitivity through signal amplification and allows for greater flexibility for labeling and detection.


Isotype controls are primary antibodies that lack specificity to a target, however they match the class and type of the primary antibody being used. Isotype controls are used as negative controls to help distinguish nonspecific background signal from specific antibody signal. When selecting an isotype control you should match the antibody’s host species and class. If using a primary conjugated antibody, it is important to use the same conjugation for the isotype control.

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Recombinant rabbit monoclonal antibodies provide a variety of unique benefits for Western blot, IHC, and other experiments.


The production of monoclonal antibodies dates back to 1975 when Köhler and Milstein first described the fusion of immunized mouse spleen B cells with cancerous myeloma cells, resulting in hybridoma cells that are both immortal and secrete a specific antibody of interest.

Despite the reproducibility and specificity that mouse monoclonal antibodies deliver, they have limited sensitivity and are susceptible to antigen heterogeneity and experimental condition changes.

Rabbit monoclonal antibodies have emerged in recent years as a crucial subset of the research antibody market.

Spurred by early successes as in vitro diagnostics — in addition to ongoing trials for therapeutic applications — rabbit monoclonal antibodies are increasingly being used for research in the life sciences as well. Scientists recognize the unique qualities these antibodies hold, such as broader reactivity with commonly studied animal tissue and a stronger, more diverse immune response when compared to mouse-derived antibodies.
While the breadth and depth of products have not yet matched traditional mouse monoclonal antibody catalogues, the scientific community’s demand for more accurate, reliable reagents ensures the continued expansion of this market.

How do I reconstitute my antibody?

If you received the antibody in liquid form, it is ready to use; no reconstitution needed. Reconstitution is only required for a lyophilized antibody. Please refer to the reconstitution instructions on the data sheet included in the package.

Should I make aliquots of my antibody?

Yes, we strongly recommend making aliquots once the antibody is reconstituted in order to avoid repeated freeze/thaw cycles.

Where do I store my antibody?

You should store unconjugated antibodies at -20C. All conjugated antibodies should be stored at 4C.

Do you provide commercial buffers to customers?

Unfortunately, we currently do not have buffers in our catalog.

What is the antibody made in?

Every Bioss antibody is made with BSA, sodium azide, and PBS.

Can these antibodies be made without preservatives?

Yes! Please send us an email and our support team will respond within 1 business day to let you know if the antibody you are interested is available without preservatives:

How do you choose an isotype control?

2 simple steps: Match the IgG and Conjugation. For example, If you are using IgG1 PE antibody, find an IgG1 and PE conjugated isotype control.

Do you offer the antigen or blocking peptide?

At this time, Bioss does not offer blocking peptides. If you need detailed immunogen information contact our support team:

What is the isotype of this antibody?

We currently offer various isotypes. Please check the datasheet for more information.

After reconstitution in 100ul, the concentration is 1 ug/ul. Is this the total protein concentration or the concentration of the IgG?

The concentration of IgG.

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